alzheimer's disease (ad) is a chronic neurodegenerative disease that accounts for 60 to 80 percent of all dementia cases. the exact cause of alzheimer`s disease is still unknown, but recent studies suggest neuro-inflammation as an important part of the pathogenesis of the disease. this brings in mind using non-steroidal anti-inflammatory drugs (nsaid) as treatment or prevention of the dise...

in the present study, the usage pattern of anti-inflammatory drugs-steroidal and non-steroidal- in patients referred to 13 aban pharmacy in sari was evaluated. the results show a high rate of anti-inflammatory drug prescriptions, mainly by general practitioners with ibuprofen, diclofenac and mefenamic acid being the most widely used nsaids and prednisolone, dexamethasone and betamethasone being...

introduction: post-endodontic pain is one of the main problems for both patients and dentists. the purpose of this study was to compare the effectiveness of premedication with indomethacin and ibuprofen for management of postoperative endodontic pain. methods and materials: in this clinical trial, mandibular molars with irreversible pulpitis were endodontically treated in 66 patients. the medic...

background: peritendinous adhesions after repairing an injury to the digital flexor tendons are a major problem in hand surgery. non-steroidal anti-inflammatory drug therapy may affect tendon healing and the development of peritendinous adhesions. the aim of this study was to evaluate ibuprofen effect in patients function after flexor tendon surgical repair.   method: thirty-five patients, who ...

background: although helicobacter pylori and non-steroidal anti-inflammatory drugs (nsaids) are the main causes of peptic ulcers disease (pud), recently the prevalence of idiopathic peptic ulcer (ipu) is increasing in most parts of the world. the aim of this study was to assess the prevalence of ipu in kerman, the center of largest province in south-east iran. methods : we included 215 patients...

background: evidences show that aloe vera (a. vera), camellia sinensis, hibiscus sabdariffa and sophora alopecuroides may prevent gastric ulcer induced by non-steroidal anti-inflammatory drugs (nsaids). objective: to examine the protective potential of these plants against indomethacin-induced gastric ulcer in the rat. methods: saline, a. vera leaf gel powder and 70% alcoholic extracts of the o...

BACKGROUND Non-steroidal anti-inflammatory drugs have been implicated in reports of liver injury. However, the precise risk of non-steroidal anti-inflammatory drugs for this rare complication is unknown. AIM To review systematically the published literature of population-based epidemiological studies reporting the incidence or comparative risk of non-steroidal anti-inflammatory drugs for live...

Non-steroidal anti-inflammatory drugs are the most commonly prescribed drugs for arthritis, inflammation, and cardiovascular protection. However, they cause gastrointestinal complications. The pathophysiology of these complications has mostly been ascribed to non-steroidal anti-inflammatory drugs' action on the cyclooxygenase inhibition and the subsequent prostaglandin deficiency. However, rece...